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Rotigotine (Neupro), a new non-ergolinic dopamine agonist in a transdermal patch, for early and late stages of Parkinson's disease.

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Subcutaneous injections or continuous infusions have been found useful even in advanced PD by reducing the “off” time without necessarily increasing dyskinesias ().

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The results of the oft-cited Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) demonstrated that FGAs and SGAs have similar efficacy, but both groups have potentially troublesome side effects that warrant careful monitoring and can disrupt otherwise effective treatment.

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